Eosinophilia in Hematologic Disorders

Abnormal ("ringed") sideroblasts in various hematologic and non-hematologic disorders.

Parvovirus-B19 and hematologic disorders.

Parvovirus-B19 (PV-B19) is a member of Parvoviridae, which is one of the smallest DNA viruses. PV-B19-associated diseases usually serve as a good representation of the balance of virus, host response and the immune system. The diseases manifested with PV-B19 are erythema infectiosum, which is common in children, hydrops fetalis, transient pure red cell aplasia in patients with chronic hemolytic...

Chapter 7: Hematologic Disorders and Kidney Disease

Pathogenesis Multiple myeloma (MM) is a hematologic malignancy involving the pathologic proliferation of terminally differentiated plasma cells. It is the second most common hematologic malignancy behind non-Hodgkin lymphoma, with an annual incidence of 4–7 cases per 100,000 in the United States. Clinical symptoms are due to osteolysis of the bone, suppression of normal hematopoiesis, and the o...

Vascular complications after splenectomy for hematologic disorders.

The most widely recognized long-term risk of splenectomy is overwhelming bacterial infection. More recently, thrombosis has become appreciated as another potential complication of the procedure. Because of these long-term risks, the indications for and timing of splenectomy are debated in the medical community. Accordingly, the adverse effects and benefits of splenectomy for hematologic disorde...

Hematologic disorders after solid organ transplantation.

The evaluation of hematologic disorders after solid organ transplantation (SOT) must take into account issues unique to the post-transplant setting that influence the development of anemia and single or multi-lineage cytopenias. Attention to the time of onset of cytopenia(s) is important, because the disorders of passenger lymphocyte syndrome, transplant-related thrombotic microangiopathy, hemo...